PFKFB2 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 17838-1-AP

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 20 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat

Positive WB detected in:
human heart tissue, mouse brain tissue, rat brain tissue

Positive IHC detected in:
human spleen tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

Calculated molecular weight:
505aa,58 kDa

Observed molecular weight:
58 kDa, 110 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PFKFB2

Synonyms
6PF 2 K/Fru 2,6 P2ase 2, DKFZp781D2217, PFK 2/FBPase 2, PFK/FBPase 2, PFKFB2
Background

PFKFB2(6-Phosphofructo-2-kinase/fructose 2,6-bisphosphatase 2) is also named as PFK-2/FBPase-2, which is a bifunctional enzyme responsible for the synthesis and breakdown of Fru-2,6-P2, a key metabolite in the regulation of glycolysis(PMID:10095107). In the C-terminal section, it belongs to the phosphoglycerate mutase family.The enzyme is a dimer of identical subunits, each composed of 505 amino acids and containing three discrete domains(PMID: 2552438). It has 2 isoforms produced by alternative splicing.


Back
to top