PFKFB2 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 17838-1-AP

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Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human heart tissue, mouse brain tissue, rat brain tissue

Positive IHC detected in:
human spleen tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

Calculated molecular weight:
505aa,58 kDa

Observed molecular weight:
58 kDa, 110 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

6PF 2 K/Fru 2,6 P2ase 2, PFK 2/FBPase 2, PFK/FBPase 2, PFKFB2

PFKFB2(6-Phosphofructo-2-kinase/fructose 2,6-bisphosphatase 2) is also named as PFK-2/FBPase-2, which is a bifunctional enzyme responsible for the synthesis and breakdown of Fru-2,6-P2, a key metabolite in the regulation of glycolysis(PMID:10095107). In the C-terminal section, it belongs to the phosphoglycerate mutase family.The enzyme is a dimer of identical subunits, each composed of 505 amino acids and containing three discrete domains(PMID: 2552438). It has 2 isoforms produced by alternative splicing.

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