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|Author:||Miranda B Carper|
RGS16, a novel p53 and pRb cross-talk candidate inhibits migration and invasion of pancreatic cancer cells.
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RGS16 belongs to the 'regulator of G protein signaling' family. The RGS proteins are a family of highly diverse, multifunctional signaling proteins found in eukaryotic species ranging from yeast to mammals. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade.