RRM2 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 11661-1-AP

  • Print page
  • Download PDF

Be the first to review this product



Con: 37 μg/150 μl

Choose size:

Please visit your regions distributor:

Species specificity:
human, mouse, rat

Positive WB detected in:
K-562 cells, A431 cells, HeLa cells,

Positive IP detected in:
K-562 cells

Positive IHC detected in:
human tonsillitis tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
ribonucleotide reductase M2 polypeptide

Calculated molecular weight:
389aa,45 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol

R2, RR2, RR2M, RRM2

Ribonucleotide reductase M2 subunit is one of two subunits that constitute ribonucleotide reductase, the enzyme that catalyzes the conversion of ribonucleotide 5'-diphosphates into 2'-deoxyribonucleotides, a rate-limiting step in the production of 2'-deoxyribonucleoside 5'-diphosphates (dNTP) required for DNA synthesis and repair that is required for DNA synthesis and repair [PMID:20825972, 19250552]. RRM2 is only expressed during the late G1/early S phase, and degraded in late S phase, and the activity of RNR, and therefore DNA synthesis and cell proliferation, is controlled during the cell cycle by the synthesis and degradation of RRM2 subunit [PMID:3894352].

to top