SEC24A Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 15958-1-AP

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Con: 30 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human liver tissue, mouse skeletal muscle tissue, mouse thymus tissue, rat thymus tissue

Positive IHC detected in:
human lymphoma tissue

Positive IF detected in:
Hela cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
SEC24 family, member A (S. cerevisiae)

Calculated molecular weight:
613aa,66 kDa

Observed molecular weight:
66 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SEC24A

Synonyms
SEC24 related protein A, SEC24A
Background

COPII-coated vesicles mediate anterograde transport from the ER to the Golgi apparatus. COPII is composed of three parts: two coat protein complexes (Sec23/24 complex and Sec13/31 complex) and one small GTP-binding protein, Sar1 (PMID: 9568718). Sec24 subunit of the coat complex has been implicated in cargo recognition (PMID: 17316621). In mammal cells there are four Sec24 isoforms, termed Sec24A, Sec24B, Sec24C, and Sec24D (PMID: 10329445).


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