SEC31A Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 17913-1-AP

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Con: 50 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, Jurkat cells

Positive IP detected in:
HeLa cells

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
SEC31 homolog A (S. cerevisiae)

Calculated molecular weight:
1220aa,133 kDa

Observed molecular weight:
133 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SEC31A

Synonyms
ABP125, ABP130, DKFZp686N07171, HSPC275, HSPC334, KIAA0905, SEC31 like protein 1, SEC31 related protein A, SEC31A, SEC31L1, Web1 like protein
Background

COPII-coated vesicles mediate anterograde transport from the ER to the Golgi apparatus. COPII is composed of three parts: two coat protein complexes (Sec23/24 complex and Sec13/31 complex) and one small GTP-binding protein, Sar1 (PMID: 9568718). Sec31 subunit of the coat complex has been shown to be essential for vesicle formation and ER-Golgi transport (PMID: 10788476). Two mammalian homologues of yeast sec31p, Sec31A and Sec31B, share about 40% amino acid identity. Sec31A transcripts are ubiquitously and abundantly expressed.


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