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Tested Applications
| Positive WB detected in | A549 cells, Jurkat cells, MCF-7 cells, mouse spleen tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 1 publications below |
| IHC | See 1 publications below |
Product Information
20693-1-AP targets TNFAIP8L3 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | tumor necrosis factor, alpha-induced protein 8-like 3 |
| Calculated Molecular Weight | 33 kDa |
| Observed Molecular Weight | 37 kDa |
| GenBank Accession Number | NM_207381 |
| Gene Symbol | TNFAIP8L3 |
| Gene ID (NCBI) | 388121 |
| RRID | AB_3085613 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q5GJ75 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
TNFAIP8L3 (tumor necrosis factor alpha-induced protein 8-like protein 3), also known as TIPE3, is a member of the TNFAIP8 family which also include TNFAIP8 (TIPE), TNFAIP8L1 (TIPE1) and TNFAIP8L2 (TIPE2) (PMID: 18455983; 21924498). TNFAIP8L3 is a transfer protein for phosphoinositide second messengers. It is markedly upregulated in human cancer cells and may represent a therapeutic target for treating malignant diseases (PMID: 25242044). This antibody is specific to TNFAIP8L3.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for TNFAIP8L3 antibody 20693-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Hum Mol Genet CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10. | ||
Cell Death Discov TIPE3 promotes drug resistance in colorectal cancer by enhancing autophagy via the USP19/Beclin1 pathway |
