CD134/OX40 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 20006-1-AP

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Freight/Packing

Con: 38 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HepG2 cells, K-562 cells, L02 cells, U-937 cells

Positive FC detected in:
U-937 cells

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
tumor necrosis factor receptor superfamily, member 4

Calculated molecular weight:
29 kDa

Observed molecular weight:
43 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TNFRSF4

Synonyms
ACT35, ACT35 antigen, CD134, OX40, OX40L receptor, TNFRSF4, TXGP1L
Background

CD134 (OX40) is a member of the TNFR-superfamily of receptors. Predominantly expressed on activated T cells, CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule. CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmunity (PMID: 26215166). CD134 can interact with TRAF2, TRAF3, and TRAF5.


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