UCHL1 Antibody 1 Publications

Mouse Monoclonal| Catalog number: 66230-1-Ig |CloneNo.: 1C9E11

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 225 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, pig, rat

Positive WB detected in:
Y79 cells, PC-12 cells

Positive IHC detected in:
human hypothalamus tissue,human brain tissue, mouse brain tissue

Positive IF detected in:
SH-SY5Y cells

Recommended dilution:
WB : 1:1000-1:50000
IHC : 1:200-1:2000
IF : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

Calculated molecular weight:
25 kDa

Observed molecular weight:
27 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
UCHL1

Synonyms
Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1, Uch L1, UCHL1
Background

UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons(PMID: 6343558). This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm (PMID:7217993). And UCHL1 is a Parkinson's disease susceptibility gene (PMID:15048890).


Back
to top