ULK1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 20986-1-AP

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Con: 52 μg/150 μl

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Species specificity:
human, rat

Positive WB detected in:
rat skeletal muscle tissue

Positive IHC detected in:
human skeletal muscle tissue, human liver tissue, human skeletal muscle tissue

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
unc-51-like kinase 1 (C. elegans)

Calculated molecular weight:
113 kDa

Observed molecular weight:
150 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ULK1

Synonyms
ATG1, FLJ38455, FLJ46475, KIAA0722, ULK1, Unc 51 like kinase 1, UNC51, Unc51.1
Background

ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase (FAK) family interacting protein of 200 kDa (FIP 200)(PMID:21460634). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC(PMID:23573318).


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