TAZ Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 23306-1-AP

Featured Product KD/KO validated

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Con: 69 μg/150 μl

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Species specificity:

Positive WB detected in:
MDA-MB-453s cells, HeLa cells, LN229 cells

Positive IP detected in:
MDA-MB-453s cells

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, human heart tissue, human thyroid cancer tissue

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:50-1:500

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
WW domain containing transcription regulator 1

Calculated molecular weight:
44 kDa

Observed molecular weight:
50 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

DKFZp586I1419, TAZ, WWTR1

TAZ, also referred as WWTR1, is a transcriptional co-activator with a PDZ-binding motif that is regulated by its interaction with 14-3-3 protein. TAZ is expressed in many primary tumors, such as breast cancer, thyroid carcinoma, colorectal cancer, and glioma. TAZ has been reported to be one of the nuclear effectors of Hippo-related pathways that regulate organ size control, cancer stem cell (CSC) properties, and epithelial–mesenchymal transition (EMT). TAZ has been defined for its role in the nucleus, where it functions directly as a transcriptional regulator by interacting with several nuclear factors as Runx2/Cbfa1, NHERF-2, TEF-1, TBX5, PAX3, PAX8 and TTF-1.

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