p38 MAPK Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66234-1-Ig |CloneNo.: 1A1C2

Featured Product KD/KO validated

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Freight/Packing

Con: 200 μg/150 μl

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Species specificity:
human, pig

Positive WB detected in:
human heart tissue, HEK-293 cells, pig heart tissue

Positive IHC detected in:
human gliomas tissue, human lung cancer tissue

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:100-1:400

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
mitogen-activated protein kinase 14

Calculated molecular weight:
360aa,41 kDa

Observed molecular weight:
38-42 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MAPK14

Synonyms
CSAID binding protein, CSBP, CSBP1, CSBP2, CSPB1, EXIP, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, MAPK 14, MAPK14, MAX interacting protein 2, Mxi2, p38, p38 MAPK, p38ALPHA, PRKM14, PRKM15, RK, SAPK2A
Background

MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.


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