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  • Validé par KD/KO

Anticorps Polyclonal de lapin anti-APJ/APLNR

APJ/APLNR Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris et plus (2)

Applications

WB, IHC, IF, ELISA

Conjugaison

Non conjugué

Publications(48)

N° de cat : 20341-1-AP

Synonymes

APJ, AGTRL1, Angiotensin receptor-like 1, APLNR, G-protein coupled receptor APJ



Applications testées

Résultats positifs en WBcellules SH-SY5Y
Résultats positifs en FC (Intra)cellules SH-SY5Y,

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Flow Cytometry (FC) (INTRA)FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

20341-1-AP cible APJ/APLNR dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Réactivité citéerat, Humain, Lapin, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène APJ/APLNR Protéine recombinante Ag14138
Nom complet apelin receptor
Masse moléculaire calculée 380 aa, 43 kDa
Poids moléculaire observé 43 kDa
Numéro d’acquisition GenBankBC032688
Symbole du gène APJ
Identification du gène (NCBI) 187
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS with 0.02% sodium azide and 50% glycerol
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

APJ, also named APLNR and AGTRL1, belongs to the G-protein coupled receptor 1 family. It is a receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. APJ is an alternative coreceptor with CD4 for HIV-1 infection. It may be involved in the development of AIDS dementia. APJ is expressed abundantly in the corpus callosum and spinal cord.

Protocole

Product Specific Protocols
WB protocol for APJ/APLNR antibody 20341-1-APDownload protocol
FC protocol for APJ/APLNR antibody 20341-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIF

Immunity

Single-cell atlas of endothelial and mural cells across primary and metastatic brain tumors

Authors - Leire Bejarano
mouseIHC

Cell Metab

Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis.

Authors - Katerina Rohlenova
mouseIF

Sci Transl Med

Apelin stimulation of the vascular skeletal muscle stem cell niche enhances endogenous repair in dystrophic mice

Authors - Emmeran Le Moal
mouseIF

Nat Commun

Molecular determinants of nephron vascular specialization in the kidney.

Authors - David M Barry
mouseWB

Int J Nanomedicine

Apelin-13-Loaded Macrophage Membrane-Encapsulated Nanoparticles for Targeted Ischemic Stroke Therapy via Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis

Authors - Chang-Sheng Ma
mouse,humanWB

Free Radic Biol Med

The Elabela-APJ axis attenuates sepsis-induced myocardial dysfunction by reducing pyroptosis by balancing the formation and degradation of autophagosomes

Authors - Shuai Liu

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.


FH

Nicole (Verified Customer) (02-24-2022)

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:500
  • Cell Tissue Type: HEK cells
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