Product Information
83223-4-PBS targets Nectin-4/PVRL4 in IF/ICC, FC, Cytometric bead array, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Affinity | KD=2.28 x 10-10M KOff=2.98 x 10-5M KOn=2.62 x 105M |
Immunogen | Nectin-4/PVRL4 fusion protein Eg0415 Predict reactive species |
Full Name | poliovirus receptor-related 4 |
Calculated Molecular Weight | 510 aa, 55 kDa |
GenBank Accession Number | BC010423 |
Gene Symbol | Nectin-4 |
Gene ID (NCBI) | 81607 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q96NY8 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
Nectin-4, or PVRL4, belongs to the family of cell adhesion molecules that regulate the formation of adherence functions in epithelial cells through the AF-6 afadin scaffold molecule. Nectin-4 is reported as a histological and serological marker for breast carcinoma. Nectin-4 can be detected as a soluble form of 43 kDa and a transmembrane form of 66 kDa (PMID: 15784625).