Recombinant Human CXCL6 protein (rFc Tag)
Species
Human
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg3386
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Human CXCL6 protein Gly38-Asn114 (Accession# P80162) with a rabbit IgG Fc tag at the N-terminus. |
| GeneID | 6372 |
| Accession | P80162 |
| PredictedSize | 35.5 kDa |
| SDS-PAGE | 35-45 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in 30mM Tris, 500mM arginine, pH 8.0. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
Chemokine (C-X-C motif) ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family that is also known as granulocyte chemotactic protein 2 (GCP-2). As its former name suggests, CXCL6 is a chemoattractant for neutrophilic granulocytes. It elicits its chemotactic effects by interacting with the chemokine receptors CXCR1 and CXCR2.The gene for CXCL6 is located on human chromosome 4 in a cluster with other CXC chemokine genes.
References:
1. Proost P, Wuyts A, Conings R, et al. (1993) Biochemistry.32(38):10170-10177. 2. Wuyts A, Van Osselaer N, Haelens A, et al. (1997) Biochemistry.36(9):2716-2723. 3. Modi WS, Chen ZQ. (1998) Genomics.47(1):136-139. 4. O'Donovan N, Galvin M, Morgan JG.(1999) Cytogenet Cell Genet.84(1-2):39-42.