Anti-Human ADAMTS13 Rabbit Recombinant Antibody

ADAMTS13 Uni-rAbTM Recombinant Antibody for FC (Intra)

Cat No. 98468-2-RR
Clone No.250498C4

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC (Intra)

ADAM TS 13, ADAM TS13, ADAMTS 13, C9orf8, TTP

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive FC (Intra) detected inHUVEC cells

Recommended dilution

ApplicationDilution
Flow Cytometry (FC) (INTRA)FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

98468-2-RR targets ADAMTS13 in FC (Intra) applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen ADAMTS13 fusion protein Eg2556 Predict reactive species
Full Name ADAM metallopeptidase with thrombospondin type 1 motif, 13
Calculated Molecular Weight 154 kDa
GenBank Accession NumberNM_139025
Gene Symbol ADAMTS13
Gene ID (NCBI) 11093
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ76LX8
Storage Buffer PBS with 0.09% sodium azide, pH 7.3.
Storage ConditionsStore at 2 - 8°C. Stable for one year after shipment.

Background Information

ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin type 1 motifs, member 13) is a zinc-dependent metalloproteinase that contains multiple domains, such as the signal peptide, propeptide, metalloproteinase domain, disintegrin-like domain, and TSP-1 domain, among others. The primary function of ADAMTS13 is to specifically cleave the ultra-large multimers of von Willebrand factor (vWF), preventing excessive platelet aggregation and the formation of microvascular thrombi. Deficiency of ADAMTS13 is closely associated with thrombotic thrombocytopenic purpura (TTP), a severe disease characterized by thrombocytopenia, microvascular thrombosis, and tissue damage. Additionally, reduced ADAMTS13 activity is also linked to diseases such as myocardial infarction and stroke.

Protocols

Product Specific Protocols
FC protocol for ADAMTS13 antibody 98468-2-RRDownload protocol
Standard Protocols
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