ADAMTS4 Recombinant antibody, PBS Only

ADAMTS4 Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG


Human, Mouse, Rat


WB, Indirect ELISA





Cat no : 82744-2-PBS


ADAM TS 4, ADAM TS4, ADAMTS 2, ADAMTS 4, ADAMTS4, ADMP 1, Aggrecanase 1, KIAA0688

Recommended dilution

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

82744-2-PBS targets ADAMTS4 in WB, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.

Tested Reactivity Human, Mouse, Rat
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen ADAMTS4 fusion protein Ag2443
Full Name ADAM metallopeptidase with thrombospondin type 1 motif, 4
Calculated Molecular Weight 837 aa, 90 kDa
Observed Molecular Weight 90 kDa
GenBank Accession NumberBC030812
Gene Symbol ADAMTS4
Gene ID (NCBI) 9507
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

The ADAMTS (a disintegrin-like and metalloproteinase with thrombospondin motifs) is a family of extracellular metalloproteinases mediating diverse functions including matrix degradation, blood coagulation and angiogenesis. The ADAMTS family constitutes a group of proteins composed of 19 enzymes and 7 ADAMTS-like proteins. ADAMTS4 is a well-known proteoglycanase and has angiomodulatory properties. The 837 amino acid long human ADAMTS4 protein contains a long signal peptide, a prodomain, a metalloproteinase catalytic domain with zinc-binding motif, a disintegrin-like domain, a central TSR motif, followed by a cysteine-rich region with ten conserved cysteine residues, and a spacer domain. The full-length proform human ADAMTS4 (zymogen form) has been described to be 90 kDa. In extracellular matrix (ECM), ADAMTS4 undergoes further C-terminal cleavage at Lys694-Phe695 and Thr581-Phe582, respectively, to generate two other truncated forms-53 and 40 kDa (PMID:12202483).