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- KD/KO Validated
Adiponectin receptor Polyclonal antibody
Adiponectin receptor Polyclonal Antibody for IP, WB,ELISA
Cat no : 14361-1-AP
|Positive WB detected in||L02 cells, HeLa cells, mouse uterus tissue|
|Positive IP detected in||HeLa cells|
|Western Blot (WB)||WB : 1:500-1:1000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB|
|Sample-dependent, check data in validation data gallery|
14361-1-AP targets Adiponectin receptor in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||hamster, human, mouse, pig, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Adiponectin receptor fusion protein Ag5744|
|Full Name||adiponectin receptor 2|
|Calculated molecular weight||44 kDa|
|Observed molecular weight||44-50 kDa|
|GenBank accession number||BC051858|
|Gene ID (NCBI)||79602|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Two receptors for adiponectin (ADIPOR1 and ADIPOR2) have been identified. They mediate increased AMPK, MAPK and PPARA ligand activity in response to adiponectin. AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. The human ADIPOR2 gene maps to chromosome 12p13.31, and encodes a 386-amino acid protein with a molecular weight of 44 kDa. This antibody raised against 1-147aa of human AdipoR2 may cross-react with AdipoR1.
Int J Biol Sci
Adiponectin Suppresses Human Pancreatic Cancer Growth through Attenuating the β-Catenin Signaling Pathway.
Butyrate alleviates high fat diet-induced obesity through activation of adiponectin-mediated pathway and stimulation of mitochondrial function in the skeletal muscle of mice.
Leucine regulates porcine muscle fiber type transformation via adiponectin signaling pathway.
Effect of dietary leucine supplementation on skeletal muscle fiber type transformation in weaning piglets
A stem cell based in vitro model of NAFLD enables the analysis of patient specific individual metabolic adaptations in response to a high fat diet and AdipoRon interference.
Effects of a low-fat diet on the hepatic expression of adiponectin and its receptors in rats with NAFLD.