• Featured Product
  • KD/KO Validated

AMOTL2 Polyclonal antibody

AMOTL2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG







Cat no : 23351-1-AP


AMOTL2, angiomotin like 2, Angiomotin like protein 2, KIAA0989, LCCP, Leman coiled coil protein

Tested Applications

Positive WB detected inHEK-293 cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Product Information

23351-1-AP targets AMOTL2 in WB, IF, CoIP, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen AMOTL2 fusion protein Ag19953
Full Name angiomotin like 2
Calculated molecular weight 779 aa, 86 kDa
Observed molecular weight 100 kDa
GenBank accession numberBC011454
Gene symbol AMOTL2
Gene ID (NCBI) 51421
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Angiomotin‑like 2 (AMOTL2) is a member of the motin family of angiostatin‑binding proteins. The motin family, also known as AMOTs, consists of three members: AMOT, AMOT-like 1 (AMOTL1) and AMOTL2. Members of the motin family are a type of adaptor proteins mainly distributed in the cytomembrane, cytoplasm or nucleus, and have a higher expression in the endothelial cells of capillaries and in larger vessels of the placenta.(PMID: 34036399,PMID: 25080976)


Product Specific Protocols
WB protocol for AMOTL2 antibody 23351-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Mol Ther Nucleic Acids

Hsa_circ_0024093 accelerates VSMC proliferation via miR-4677-3p/miR-889-3p/USP9X/YAP1 axis in in vitro model of lower extremity ASO.

Authors - Xue Zhang

Mol Ther Nucleic Acids

Hypoxic Tumor-Derived Exosomal Long Noncoding RNA UCA1 Promotes Angiogenesis via miR-96-5p/AMOTL2 in Pancreatic Cancer.

Authors - Zengya Guo
  • KD Validated

Arthritis Res Ther

Regulation of type I interferon signature by VGLL3 in the fibroblast-like synoviocytes of rheumatoid arthritis patients via targeting the Hippo pathway

Authors - Yu Du

Sci Rep

MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis.

Authors - Diala Kantar
  • KD Validated

Mol Biol Cell

AMOT130 drives BMP-SMAD signaling at the apical membrane in polarized cells.

Authors - Patrizia Brunner
  • KD Validated

Pharmaceuticals (Basel)

Comparative Assessment and High-Throughput Drug-Combination Profiling of TEAD-Palmitoylation Inhibitors in Hippo Pathway Deficient Mesothelioma

Authors - Lale Evsen


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Florian (Verified Customer) (10-13-2021)

10% SDS-PAGE 1st AB incubation ON

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:500
  • Cell Tissue Type: Human breast cancer cell line (HCC1806)
AMOTL2 Antibody Western Blot validation (1:500 dilution) in Human breast cancer cell line (HCC1806) (Cat no:23351-1-AP)

Lisa (Verified Customer) (07-08-2020)

Two specific bands (60 and 100 kDa) and two others non specific.This antibody is working by WB.

  • Applications: Western Blot
  • Primary Antibody Dilution: 1/600
  • Cell Tissue Type: MCF7 cell line
AMOTL2 Antibody Western Blot validation (1/600 dilution) in MCF7 cell line (Cat no:23351-1-AP)