|Positive WB detected in
|Western Blot (WB)
|WB : 1:500-1:1000
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
23351-1-AP targets AMOTL2 in WB, IF, CoIP, ELISA applications and shows reactivity with human samples.
|Host / Isotype
|Rabbit / IgG
|AMOTL2 fusion protein Ag19953
|angiomotin like 2
|Calculated molecular weight
|779 aa, 86 kDa
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|Antigen affinity purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
Angiomotin‑like 2 (AMOTL2) is a member of the motin family of angiostatin‑binding proteins. The motin family, also known as AMOTs, consists of three members: AMOT, AMOT-like 1 (AMOTL1) and AMOTL2. Members of the motin family are a type of adaptor proteins mainly distributed in the cytomembrane, cytoplasm or nucleus, and have a higher expression in the endothelial cells of capillaries and in larger vessels of the placenta.(PMID: 34036399,PMID: 25080976)
Mol Ther Nucleic Acids
Hsa_circ_0024093 accelerates VSMC proliferation via miR-4677-3p/miR-889-3p/USP9X/YAP1 axis in in vitro model of lower extremity ASO.
Mol Ther Nucleic Acids
Hypoxic Tumor-Derived Exosomal Long Noncoding RNA UCA1 Promotes Angiogenesis via miR-96-5p/AMOTL2 in Pancreatic Cancer.
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Regulation of type I interferon signature by VGLL3 in the fibroblast-like synoviocytes of rheumatoid arthritis patients via targeting the Hippo pathway
MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis.
Mol Biol Cell
AMOT130 drives BMP-SMAD signaling at the apical membrane in polarized cells.
Comparative Assessment and High-Throughput Drug-Combination Profiling of TEAD-Palmitoylation Inhibitors in Hippo Pathway Deficient Mesothelioma
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Florian (Verified Customer) (10-13-2021)
10% SDS-PAGE 1st AB incubation ON
Lisa (Verified Customer) (07-08-2020)
Two specific bands (60 and 100 kDa) and two others non specific.This antibody is working by WB.