• Featured Product
  • KD/KO Validated

ANGPTL7 Polyclonal antibody

ANGPTL7 Polyclonal Antibody for IF, IHC, WB, ELISA

Host / Isotype

Rabbit / IgG


human and More (1)





Cat no : 10396-1-AP


angiopoietin like 7, Angiopoietin like factor, Angiopoietin like protein 7, Angiopoietin related protein 7, ANGPTL7, AngX, CDT6, RP4 647M16.2

Tested Applications

Positive WB detected inHepG2 cells, MCF-7 cells
Positive IHC detected inhuman liver cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inTHP-1 cells

Recommended dilution

Western Blot (WB)WB : 1:1000-1:6000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10396-1-AP targets ANGPTL7 in WB, IHC, IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ANGPTL7 fusion protein Ag0596
Full Name angiopoietin-like 7
Calculated Molecular Weight 40 kDa
Observed Molecular Weight 45 kDa
GenBank Accession NumberBC001881
Gene Symbol ANGPTL7
Gene ID (NCBI) 10218
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ANGPTL7, also named as CDT6, is a member of the angiopoietin-like (ANGPTL) family of proteins, which are important regulators of Angiogenesis. It is a secreted 45-kDa glycoprotein that folds into a homotetramer structure linked by disulfide bonds. ANGPTL7 was originally discovered in the stromal layer of the corne, and moderately expressed in the human trabecular meshwork. The chromosomal location of the ANGPTL7 gene (1p36.22) is within the GLC3B locus (1p36.2-1p36.1) of primary congenital glaucoma, supporting ANGPTL7 as a candidate glaucoma gene. ANGPTL7 could have a pathogenic role in glaucoma, and may serve as a potential therapeutic target.


Product Specific Protocols
WB protocol for ANGPTL7 antibody 10396-1-APDownload protocol
IHC protocol for ANGPTL7 antibody 10396-1-APDownload protocol
IF protocol for ANGPTL7 antibody 10396-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols




Angptl7 promotes insulin resistance and type 2 diabetes mellitus by multiple mechanisms including SOCS3-mediated IRS1 degradation.

Authors - Tong Xu
  • KD Validated

Osteoarthritis Cartilage

Effects of mechanical stress and deficiency of dihydrotestosterone or 17β-estradiol on Temporomandibular Joint Osteoarthritis in mice.

Authors - T Ootake

Front Mol Biosci

An Extracellular Matrix-Based Signature Associated With Immune Microenvironment Predicts the Prognosis and Therapeutic Responses of Patients With Oesophageal Squamous Cell Carcinoma.

Authors - Hongpan Zhang

Genes Cells

Evidence for a role of angiopoietin-like 7 (ANGPTL7) in extracellular matrix formation of the human trabecular meshwork: implications for glaucoma.

Authors - Comes Núria N

Commun Biol

ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma

Authors - Kavita Praveen

Hum Mol Genet

Rare protective variants and glaucoma-relevant cell stressors modulate angiopoietin-like 7 expression

Authors - Inas F Aboobakar


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Kenzo (Verified Customer) (01-05-2024)

The antibody worked well for immunofluorescence on frozen mouse eye sections.

  • Applications: Immunofluorescence
  • Primary Antibody Dilution: 1:500
  • Cell Tissue Type: Eye