AP2B1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 15690-1-AP

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 31 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat

Positive WB detected in:
SH-SY5Y cells, C6 cells, K-562 cells

Positive IP detected in:
K-562 cells

Positive IF detected in:
Hela cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
adaptor-related protein complex 2, beta 1 subunit

Calculated molecular weight:
105 kDa

Observed molecular weight:
100 kDa-115 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AP2B1

Synonyms
ADTB2, AP 2 complex subunit beta, AP105B, AP2 BETA, AP2B1, Beta 2 adaptin, Beta adaptin, CLAPB1, DKFZp781K0743
Background

AP2B1 is a component of the adaptor protein complex 2 (AP-2). AP complexes are cytosolic heterotetramers that mediate the sorting of membrane proteins in the secretory and endocytic pathways. AP complexes are involved in the formation of clathrin-coated vesicles (CCVs) by recruiting the scaffold protein, clathrin. AP complexes also play a pivotal role in the cargo selection by recognizing the sorting signals within the cytoplasmic tail of integral membrane proteins. AP-2 works on the plasma membrane to internalize cargo in clathrin-mediated endocytosis.


Back
to top