APOE Polyclonal antibody

APOE Polyclonal Antibody for FC, WB, ELISA

Host / Isotype

Rabbit / IgG


human, mouse





Cat no : 18254-1-AP


AD2, Apo E, APOE, apoe4, apolipoprotein E, LPG

Tested Applications

Positive WB detected inHuH-7 cells, human plasma, mouse serum
Positive FC detected inHepG2 cells

Recommended dilution

Western Blot (WB)WB : 1:1000-1:6000
Sample-dependent, check data in validation data gallery

Product Information

18254-1-AP targets APOE in WB, IHC, IF, FC, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen APOE fusion protein Ag13070
Full Name apolipoprotein E
Calculated molecular weight 36 kDa
Observed molecular weight 34-38 kDa
GenBank accession numberBC003557
Gene symbol APOE
Gene ID (NCBI) 348
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

The apolipoprotein E (APOE) is a 299-amino acid polypeptide that mediates the binding, internalization, and catabolism of lipoprotein particles, and also serves as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. The very strong association of the APOE ɛ4 allele with AD risk and its role in the accumulation of amyloid β in brains of people and animal models solidify the biological relevance of APOE isoforms but do not provide mechanistic insight. APOE can be detected 43kDa and 69kDa dimers (PMID: 9831633).


Product Specific Protocols
WB protocol for APOE antibody 18254-1-APDownload protocol
FC protocol for APOE antibody 18254-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



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