OSCP Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 10994-1-AP

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Freight/Packing

Con: 62 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HEK-293 cells, HEK-293 cells, human kidney tissue, human placenta tissue, mouse colon tissue, mouse heart tissue, mouse liver tissue, mouse placenta tissue

Positive IHC detected in:
human heart tissue, human colon cancer tissue, human heart tissue, human testis tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit

Calculated molecular weight:
23 kDa

Observed molecular weight:
23-25kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ATP5O

Synonyms
ATP5O, ATPO, OSCP
Background

ATP5O(ATP synthase subunit O, mitochondrial) is also named as ATPO, OSCP and belongs to the ATPase delta chain family. The gene encodes the oligomycin sensitivity-conferring protein (OSCP) of ATP synthase. The predicted polypeptide is 213 amino acids long with more than 80% identity to the bovine and mouse homologs and it is expressed at highest levels in muscle and heart by the northern blot(PMID:7490082). Many studies have indicated that mitochondrial dysfunction is central to the development of most age-related human diseases including neurodegenerative diseases, cancer, and type 2 diabetes.


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