ATX3,ATXN3 Monoclonal antibody, PBS Only

ATX3,ATXN3 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2a


Human, mouse, pig


WB, IHC, Indirect ELISA





Cat no : 67057-1-PBS


AT3, ataxin 3, ATX3, ATX3,ATXN3, ATXN3, JOS, MJD, MJD1, SCA3

Recommended dilution

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

67057-1-PBS targets ATX3,ATXN3 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, mouse, pig samples.

Tested Reactivity Human, mouse, pig
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen ATX3,ATXN3 fusion protein Ag6627
Full Name ataxin 3
Calculated Molecular Weight 370 aa, 43 kDa
Observed Molecular Weight 41-45 kDa
GenBank Accession NumberBC033711
Gene Symbol ATXN3
Gene ID (NCBI) 4287
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

ATXN3, which has deubiquitinase activity and act as a component of the ubiquitin proteasome system, plays a role in transcriptional regulation and neuroprotection. ATXN3 interacts with RAD23, HHR23A and HHR23B, involves in the pathology of MJD. ATXN3 is a mixed-linkage, chain-editing enzyme and that the UIM region of ATXN3 regulates its substrate specificity. Contains an N-terminal deubiquitinating domain, called the Josephin domain, followed by 2 ubiquitin-interacting motifs (UIMs) and a polyQ tract near the C terminus. ATXN3 can be phosphorylated in a protein casein kinase-2-dependent manner, thus the MW would be larger than the predicted one.