AZGP1 Antibody 1 Publications

Mouse Monoclonal| Catalog number: 66178-1-Ig |CloneNo.: 4B8A4

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Freight/Packing

Con: 147 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human plasma tissue

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, human prostate cancer tissue, human prostate hyperplasia tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
alpha-2-glycoprotein 1, zinc-binding

Calculated molecular weight:
298aa,34 kDa

Observed molecular weight:
41 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AZGP1

Synonyms
AZGP1, ZA2G, ZAG, Zinc alpha 2 glycoprotein, Zn alpha 2 glycoprotein, Zn alpha 2 GP, ZNGP1
Background

Zinc-alpha-2-glycoprotein (AZGP1) is a 41-kDa soluble protein normally found in body fluids, functions as a lipid mobilizing factor (PMID: 19188554). It is known to be expressed in the secretory epithelia of the liver, lung, breast, GI tract and sweat glands, sharing significant structural similarity with the class I major histocompatibility complex (MHC) antigens (PMID: 3422450). AZGP1 is involved in carcinogenesis and differentiation. Altered expression of AZGP1 has been reported in breast cancer, prostate cancer and lung adenocarcinoma, hepatocellular carcinoma, pancreatic carcinoma and oral tumors (PMID: 22625427).


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