CoraLite® Plus 488-conjugated Zinc Alpha 2 Glycoprotein Monoclonal antibody

Zinc Alpha 2 Glycoprotein Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

IF

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

4B8A4

Cat no : CL488-66178

Synonyms

AZGP1, ZA2G, ZAG, Zinc alpha 2 glycoprotein, Zn alpha 2 glycoprotein, Zn alpha 2 GP, ZNGP1

---

Validation Data Gallery

• 

  IF Staining of PC-3 using CL488-66178

  Immunofluorescent analysis of (-20°C Methanol) fixed PC-3 cells using CoraLite® Plus 488 Zinc Alpha 2 Glycoprotein antibody (CL488-66178, Clone: 4B8A4 ) at dilution of 1:200.

---

Tested Applications

• Positive IF detected in: PC-3 cells

Recommended dilution

• Immunofluorescence (IF): IF : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

CL488-66178 targets Zinc Alpha 2 Glycoprotein in IF applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: Zinc Alpha 2 Glycoprotein fusion protein Ag5661
• Full Name: alpha-2-glycoprotein 1, zinc-binding
• Calculated Molecular Weight: 298 aa, 34 kDa
• Observed Molecular Weight: 41 kDa
• GenBank Accession Number: BC033830
• Gene Symbol: AZGP1
• Gene ID (NCBI): 563
• Conjugate: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission Maxima Wavelengths: 493 nm / 522 nm
• Form: Liquid
• Purification Method: Protein G purification
• Storage Buffer: PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
• Storage Conditions: Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Zinc-alpha-2-glycoprotein (AZGP1) is a 41-kDa soluble protein normally found in body fluids, functions as a lipid mobilizing factor (PMID: 19188554). It is known to be expressed in the secretory epithelia of the liver, lung, breast, GI tract and sweat glands, sharing significant structural similarity with the class I major histocompatibility complex (MHC) antigens (PMID: 3422450). AZGP1 is involved in carcinogenesis and differentiation. Altered expression of AZGP1 has been reported in breast cancer, prostate cancer and lung adenocarcinoma, hepatocellular carcinoma, pancreatic carcinoma and oral tumors (PMID: 22625427).