CAMKK2 Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 11549-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 23 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
PC-3 cells, fetal human brain tissue, HeLa cells, human brain tissue, human heart tissue, Jurkat cells

Positive IHC detected in:
human prostate cancer tissue

Positive IF detected in:
PC-3 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:100-1:400
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
calcium/calmodulin-dependent protein kinase kinase 2, beta

Calculated molecular weight:
588aa,60 kDa

Observed molecular weight:
55-60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CAMKK2

Synonyms
CaM kinase kinase 2, CaM kinase kinase beta, CaM KK 2, CaM KK beta, CAMKK, CaMKK 2, CaMKK beta, CAMKK2, CAMKKB, KIAA0787
Background

CAMKK2(calcium/calmodulin-dependent protein kinase kinase 2) is also named as CAMKKB, KIAA0787 and belongs to the protein kinase superfamily. It regulates hypothalamic production of the orexigenic hormone NPY and contributes to the regulation of energy balance. CAMKK2 in vivo reduces tumor growth suggests that reactivation of CAMKK2 by development of new drugs may be a new strategy to prolong the period to respond androgen-deprivation therapy(ADT)(PMID:22549914). It can be autophosphorylated(PMID:19369195). It has 7 isoforms produced by alternative splicing.


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