Anti-Human CD16 Rabbit Recombinant Antibody, PBS Only

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  FC experiment of human peripheral blood leukocyte using 98387-1-RR (same clone as 98387-1-PBS)

  1x10^6 human peripheral blood leukocyte were surface stained with 0.25 ug Anti-Human CD16 Rabbit RecAb (98387-1-RR, Clone:242426C2) .or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9)and PE-conjugated Goat Anti-Rabbit IgG. Cells were not fixed. This data was developed using the same antibody clone with 98387-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human peripheral blood leukocyte using 98387-1-RR (same clone as 98387-1-PBS)

  1x10^6 human peripheral blood leukocyte were surface stained with 0.25 ug Anti-Human CD16 Rabbit RecAb (98387-1-RR, Clone:242426C2)(red).or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue) and PE-conjugated Goat Anti-Rabbit IgG.Cells were not fixed. This data was developed using the same antibody clone with 98387-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human peripheral blood leukocyte using 98387-1-RR (same clone as 98387-1-PBS)

  1x10^6 human peripheral blood leukocyte were surface stained with 0.25 ug Anti-Human CD16 Rabbit RecAb (98387-1-RR, Clone:242426C2)(red).or Anti-Human CD16 (3G8) Mouse IgG2a Recombinant Antibody (65612-1-MR, Clone: 3G8 Lot:23015626)(green),or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue) and PE-conjugated Goat Anti-Rabbit IgG(red). Cells were not fixed. This data was developed using the same antibody clone with 98387-1-PBS in a different storage buffer formulation.

CD16 {ptg:Brand} Recombinant Antibody for FC

Cat No. 98387-1-PBS

Clone No.242426C2

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

CD16A, CD16a antigen, CD16-II, Fc gamma RIII, Fc gamma RIII alpha

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Product Information

98387-1-PBS targets CD16 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
• Calculated Molecular Weight: 254 aa, 29 kDa
• GenBank Accession Number: BC017865
• Gene Symbol: CD16a
• Gene ID (NCBI): 2214
• ENSEMBL Gene ID: ENSG00000203747
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P08637
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

CD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B.