CD27 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66308-1-Ig |CloneNo.: 1C1G3

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Freight/Packing

Con: 150 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human

Positive WB detected in:
Ramos cells,Daudi cells

Positive IHC detected in:
human tonsillitis tissue

Positive IF detected in:
human tonsillitis tissue

Recommended dilution:
WB : 1:2500-1:10000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
CD27 molecule

Calculated molecular weight:
29 kDa

Observed molecular weight:
45-55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CD27

Synonyms
CD27, CD27 antigen, CD27 molecule, CD27L receptor, S152, T cell activation antigen CD27, T14, TNFRSF7, Tp55
Background

CD27 (also known as TNFRSF7) is a type I glycoprotein expressed on some B cells and the majority of T cells, and is a member of the tumor necrosis factor (TNF) receptor family. CD27 is required for generation and long-term maintenance of T cell immunity (PMID: 11062504). It is a receptor for CD70 (Cd27L). Ligation of CD27 by CD70 induces strong ubiquitination of TRAF and the activation of both canonical and non-canonical NF-kappaB pathways, as well as the JNK pathway (PMID: 19426224). CD27 may also play a role in apoptosis through association with SIVA1.


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