Chromogranin A Monoclonal antibody

Chromogranin A Monoclonal Antibody for IF, IHC,ELISA

Host / Isotype

Mouse / IgG1


human, rat, pig, mouse







Cat no : 60135-1-Ig


CGA, CHGA, Chromogranin A, Pituitary secretory protein I, SP I, Vasostatin I Vasostatin 2

Tested Applications

Positive IHC detected inhuman pancreas tissue, human colon tissue, human lung cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inPC-12 cells

Recommended dilution

Immunohistochemistry (IHC)IHC : 1:5000-1:80000
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

60135-1-Ig targets Chromogranin A in WB, IHC, IF,ELISA applications and shows reactivity with human, rat, pig, mouse samples.

Tested Reactivity human, rat, pig, mouse
Cited Reactivity human, mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Chromogranin A fusion protein Ag0807
Full Name chromogranin A (parathyroid secretory protein 1)
Calculated molecular weight 51 kDa
GenBank accession numberBC006459
Gene symbol CHGA
Gene ID (NCBI) 1113
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). CgA is one of the most used tumor markers in NET's (neuroendocrine tumors) , and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors.


Product Specific Protocols
IHC protocol for Chromogranin A antibody 60135-1-IgDownload protocol
IF protocol for Chromogranin A antibody 60135-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols



STAR Protoc

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Cancer cell's neuroendocrine feature can be acquired through cell-cell fusion during cancer-neural stem cell interaction.

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