CLEC14A Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 23964-1-AP

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Con: 40 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
human heart tissue, mouse skeletal muscle tissue

Positive FC detected in:
HUVEC cells

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Rabbit

Purification method:
Antigen Affinity purified

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
C-type lectin domain family 14, member A

Calculated molecular weight:
490aa,52 kDa

Observed molecular weight:
52 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CLEC14A

Synonyms
C14orf27, CEG1, CLEC14A, EGFR 5, EGFR5
Background

CLEC14A is a single-pass type I transmembrane protein whose extracellular domain consists of a C-type lectin-like domain (CTLD), a series of epidermal growth factor-like domains, and a sushi-like domain (PMID: 23644659). CLEC14A is a member of the C-type lectin domain superfamily that also includes endosialin, thrombomodulin and CD93 (PMID: 16336259). It has been reported that CLEC14A is specifically expressed in endothelial cells and mediates cell to cell adhesion (PMID: 21095181). CLEC14A may be involved in tumor angiogenesis (PMID: 21706054; 23644659).


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