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  • KD/KO Validated

CP110 Polyclonal antibody

CP110 Polyclonal Antibody for FC, IHC, IP, WB,ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat, Canine and More (4)





Cat no : 12780-1-AP


Centrosomal protein of 110 kDa, CP110, CP110 protein, KIAA0419

Tested Applications

Positive WB detected inHEK-293T cells, HeLa cells, Jurkat cells
Positive IP detected inHeLa cells
Positive IHC detected inhuman testis tissue, human prostate cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive FC detected inHeLa cells
Planning an IF experiment? We recommend our CoraLite®488 and CoraLite®594 conjugated versions of this antibody.

Recommended dilution

Western Blot (WB)WB : 1:1000-1:6000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

12780-1-AP targets CP110 in WB, IP, IHC, IF, FC,ELISA applications and shows reactivity with human, mouse, rat, Canine samples.

Tested Reactivity human, mouse, rat, Canine
Cited Reactivity canine, Drosophila, human, mouse, rat, Xenopus, zebrafish
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CP110 fusion protein Ag3489
Full Name CP110 protein
Calculated molecular weight 991 aa, 111 kDa
Observed molecular weight 113 kDa
GenBank accession numberBC036654
Gene symbol CP110
Gene ID (NCBI) 9738
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

CP110, also named as CCP110 and KIAA0419, is an 110kDa protein. This gene is different to the gene CEP110 (geneID:11064; CNTRL). CP110 is a centriolar protein that positively regulates centrioleduplication while restricting centriole elongation and ciliogenesis. And it acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation.


Product Specific Protocols
WB protocol for CP110 antibody 12780-1-APDownload protocol
IHC protocol for CP110 antibody 12780-1-APDownload protocol
IP protocol for CP110 antibody 12780-1-APDownload protocol
FC protocol for CP110 antibody 12780-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Mol Biol Cell

PPP1R35 ensures centriole homeostasis by promoting centriole-to-centrosome conversion.

Authors - Chii Shyang Fong

Nat Commun

Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport.

Authors - Christine Insinna

Nat Commun

The Cep57-pericentrin module organizes PCM expansion and centriole engagement.

Authors - Koki Watanabe

Protein Cell

Neddylation inhibitor MLN4924 suppresses cilia formation by modulating AKT1.

Authors - Hongmei Mao

Nat Commun

Self-organization of Plk4 regulates symmetry breaking in centriole duplication.

Authors - Shohei Yamamoto

Sci Rep

CEP120 interacts with C2CD3 and Talpid3 and is required for centriole appendage assembly and ciliogenesis.

Authors - Jhih-Jie Tsai


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Sarah (Verified Customer) (02-16-2021)

Works very well for detection of CP110 protein using western blotting and immunfluorescence

  • Applications: Western Blot,Immunofluorescence
  • Primary Antibody Dilution: 1:500 (western), 1:300 (IF)
  • Cell Tissue Type: Jurkat E6.1 and HEK 293T
CP110 Antibody Western Blot,Immunofluorescence validation (1:500 (western), 1:300 (IF) dilution) in Jurkat E6.1 and HEK 293T (Cat no:12780-1-AP)

EK (Verified Customer) (05-04-2020)

works well for immunofluorescence detection of basal body localization

  • Applications: Immunofluorescence