CRNN Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 11799-1-AP

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Freight/Packing

Con: 32 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse brain tissue, HepG2 cells

Positive IHC detected in:
human oesophagus tissue, human cervical cancer tissue, human oesophagus tissue, human skin tissue

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cornulin

Calculated molecular weight:
495aa,54 kDa

Observed molecular weight:
70 kDa, 58 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CRNN

Synonyms
58 kDa heat shock protein, C1orf10, cornulin, CRNN, DRC1, PDRC1, SEP53, Tumor related protein
Background

Cornulin, also known as C1orf10, is a member of the "fused gene" family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. It may play a role in the mucosal/epithelial immune response and epidermal differentiation. Specific to squamous epithelia cells, cornulin is expressed in esophagus, primary keratinocytes, scalp skin, foreskin, cervix, larynx, and fetal bladder. It may be a marker of late epidermal differentiation, and is down-regulated in eczema.


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