|Positive WB detected in||HeLa cells, K-562 cells, HEK-293 cells|
|Positive IP detected in||HeLa cells|
|Positive IF detected in||HepG2 cells|
|Western Blot (WB)||WB : 1:500-1:3000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB|
|Immunofluorescence (IF)||IF : 1:20-1:200|
|Sample-dependent, check data in validation data gallery|
14388-1-AP targets Casein Kinase 1 Delta in WB, IP, IHC, IF applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Casein Kinase 1 Delta fusion protein Ag5856|
|Full Name||casein kinase 1, delta|
|Calculated molecular weight||47 kDa|
|Observed molecular weight||47 kDa|
|GenBank accession number||BC003558|
|Gene ID (NCBI)||1453|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
CSNK1D(casein kinase I isoform delta) is also named as HCKID, CKId and belongs to the casein kinase I subfamily. CKI is a ubiquitous enzyme which has been found in the cytosol, associated with membranes, and in the nucleus. It can phosphorylate a large number of cytosolic, membrane-associated, and nuclear proteins(PMID:8454611). CSNK1D is found to be associated generally with granulovacuolar bodies and tau-containing neurofibrillary tangles in AD, DS, PSP, PDC, PPND, and controls, and Pick bodies and ballooned neurons in PiD(PMID:10924763). It has 2 isoforms produced by alternative splicing.
|Product Specific Protocols|
|WB protocol for Casein Kinase 1 Delta antibody 14388-1-AP||Download protocol|
|IF protocol for Casein Kinase 1 Delta antibody 14388-1-AP||Download protocol|
|IP protocol for Casein Kinase 1 Delta antibody 14388-1-AP||Download protocol|
|Click here to view our Standard Protocols|
Casein Kinase 1δ/ε Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor-β in Pulmonary Fibrosis.
Front Cell Dev Biol
Casein Kinase 1 Family Member CK1δ/Hrr25 Is Required for Autophagosome Completion.
Casein kinase 1 (α, δ and ε) localize at the spindle poles, but may not be essential for mammalian oocyte meiotic progression.
Mol Cell Biol
DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase.
J Cell Biol
CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1.
Mitotic ER Exit Site Disassembly and Reassembly Are Regulated by the Phosphorylation Status of TANGO1.