CTGF Antibody 10 Publications

Rabbit Polyclonal| Catalog number: 23936-1-AP

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Freight/Packing

Con: 50 μg/150 μl

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Species specificity:
human, mouse, human; dog; miniping;rat; sheep; buffloa; pig, rat

Positive WB detected in:
mouse heart tissue, Transfected HEK-293 cells

Positive IHC detected in:
human colon cancer tissue, human colon cancer tissue, human gliomas tissue, human heart tissue, human hepatocirrhosis tissue

Positive IF detected in:
HepG2 cells, HeLa cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen Affinity purified

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
connective tissue growth factor

Calculated molecular weight:
349aa,38 kDa

Observed molecular weight:
38 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CTGF

Synonyms
CCN family member 2, CCN2, CTGF, HCS24, IBP 8, IGF binding protein 8, IGFBP 8, IGFBP8, NOV2
Background

CTGF, also known as CCN2 or connective tissue growth factor, is a member of the CCN family of matricellular proteins. CTGF, a cysteine-rich, matrix-associated, heparin-binding protein, is widely expressed in various human tissues and organs. CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair, and is critically involved in fibrotic disease and several forms of cancers. In western blotting, there are three different forms of CTGF reported: monomeric forms at approximately 36-38 kDa, homodimeric forms at approximately 70 kDa, and lower molecular mass fragment forms.


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