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CXCL1 Polyclonal antibody

CXCL1 Polyclonal Antibody for IHC, WB, ELISA

Host / Isotype

Rabbit / IgG


human and More (1)





Cat no : 12335-1-AP


C X C motif chemokine 1, CXCL1, FSP, GRO, GRO alpha(1 73), GRO1, GROa, Growth regulated alpha protein, MGSA, MGSA a, NAP 3, SCYB1

Tested Applications

Positive WB detected inLPS and Protein transport inhibitor treated HUVEC cells
Positive IHC detected inhuman gliomas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

12335-1-AP targets CXCL1 in WB, IHC, IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CXCL1 fusion protein Ag2917
Full Name chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
Calculated molecular weight 8 kDa to 14 kDa
GenBank accession numberBC011976
Gene symbol CXCL1
Gene ID (NCBI) 2919
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CXCL1 a is a member of CXC family and also known as keratinocyte-derived chemokines (KC) or growth-related oncogene (GRO). CXCL1 is expressed by macrophages, neutrophils and epithelial cells. CXCL1 binding specifically to the CXC chemokine receptor CXCR2, is involved in fibrogenesis and angiogenesis. This protein also plays a role in inflammation and as a chemoattractant for neutrophils. CXCL1 is upregulated in some types of human cancer, including colorectal, bladder, breast, prostate and skin cancers.


Product Specific Protocols
WB protocol for CXCL1 antibody 12335-1-APDownload protocol
IHC protocol for CXCL1 antibody 12335-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Cell Host Microbe

Induction of bone loss by pathobiont-mediated Nod1 signaling in the oral cavity.

Authors - Jiao Yizu Y

J Exp Med

An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition.

Authors - Helen L Young

Cell Rep

Oral microbiota affects the efficacy and prognosis of radiotherapy for colorectal cancer in mouse models

Authors - Jiali Dong


Microglial IL-1RA ameliorates brain injury after ischemic stroke by inhibiting astrocytic CXCL1-mediated neutrophil recruitment and microvessel occlusion

Authors - Xiaoyan Huang
human, mouseIHC

Kidney Int

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Clin Cancer Res

Transduction of tumor-specific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responses.

Authors - Peng Weiyi W