GRO alpha Antibody 11 Publications

Rabbit Polyclonal| Catalog number: 12335-1-AP

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Freight/Packing

Con: 32 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
COLO 320 cells,mouse small intestine tissue

Positive IHC detected in:
human ovary tumor tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

Calculated molecular weight:
8 kDa to 14 kDa

Observed molecular weight:
8 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CXCL1

Synonyms
C X C motif chemokine 1, CXCL1, FSP, GRO, GRO alpha(1 73), GRO1, GROa, Growth regulated alpha protein, MGSA, MGSA a, NAP 3, SCYB1
Background

CXCL1 a is a member of CXC family and also known as keratinocyte-derived chemokines (KC) or growth-related oncogene (GRO). CXCL1 is expressed by macrophages, neutrophils and epithelial cells. CXCL1 binding specifically to the CXC chemokine receptor CXCR2, is involved in fibrogenesis and angiogenesis. This protein also plays a role in inflammation and as a chemoattractant for neutrophils. CXCL1 is upregulated in some types of human cancer, including colorectal, bladder, breast, prostate and skin cancers.


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