Product Information
14065-1-PBS targets DAZ in WB, Indirect ELISA applications and shows reactivity with human, rat samples.
Tested Reactivity | human, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | DAZ fusion protein Ag5116 Predict reactive species |
Full Name | deleted in azoospermia 4 |
Calculated Molecular Weight | 65 kDa |
Observed Molecular Weight | 60-65 kDa |
GenBank Accession Number | BC047617 |
Gene Symbol | DAZ4 |
Gene ID (NCBI) | 57135 |
RRID | AB_2878008 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q86SG3 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
DAZ4, encoded by the DAZ gene, is an RNA-binding protein with a role in spermatogenesis. DAZ4 is a testis-specific protein that expression restricted to premeiotic germ cells, particularly in spermatogonia. Defects in DAZ4 may be a cause of spermatogenic failure Y-linked type 2 (SPGFY2). It is a disorder resulting in the absence (azoospermia) or reduction (oligozoospermia) of sperm in the semen, leading to male infertility.