FLI1 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 11347-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 80 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
HL-60 cells, human brain tissue, Jurkat cells, mouse thymus tissue

Positive IHC detected in:
human lymphoma tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
Friend leukemia virus integration 1

Calculated molecular weight:
452aa,51 kDa

Observed molecular weight:
51 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FLI1

Synonyms
EWSR2, FLI1, Proto oncogene Fli 1, SIC 1, Transcription factor ERGB
Background

Friend leukemia virus integration1 (FLI1) that is also termed EWSR2 encodes a sequence-specific transcriptional activator involved in Ewing’s sarcoma (EWS), a malignant small, round, blue cell tumour. It is a rare disease in which cancer cells are found in the bone or in soft tissue. The most common areas in which it occurs are the pelvis, the femur, the humerus, the ribs and clavicle. And EWS occurs most frequently in teenagers and young adults. FLI1 protein may act as an aberrant transcription factor, but exact mechanisms of oncogenesis remains unknown.


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