FMO5-specific Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 16864-1-AP

Featured Product KD/KO validated

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Con: 38 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
multi-cells

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, human liver tissue

Positive IF detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
flavin containing monooxygenase 5

Calculated molecular weight:
60 kDa

Observed molecular weight:
61 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FMO5

Synonyms
Dimethylaniline oxidase 5, FMO 5, FMO5
Background

Microsomal flavin-containing monooxygenases (FMOs) [dimethylaniline monooxygenase (N-oxide forming) catalyze the FAD-, NADPH- and O2-dependent oxidation of a large number of structurally diverse compounds, including drugs, pesticides, and industrial chemicals containing a soft nucleophile(PMID:12488558 ). FMO5, which belongs to the FMO family, is a lesser component of human liver microsomes and is present at about one-third the level of FMO3. FMO5 protein is also present at very low levels in kidney, however, FMO5 exhibits a severely restricted substrate specificity for most drugs and other xenobiotics examined to date(PMID:10950857). It has 2 isoforms produced by alternative splicing.


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