FYB Polyclonal antibody, PBS Only

• 

  WB analysis using 31553-1-AP (same clone as 31553-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 31553-1-AP (FYB antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31553-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary cancer using 31553-1-AP (same clone as 31553-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 31553-1-AP (FYB antibody) at dilution of 1:500 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31553-1-PBS in a different storage buffer formulation.

FYB Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 31553-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Synonyms

SLAP130, SLAP 130, p120/p130, FYB 120/130, ADAP

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Product Information

31553-1-PBS targets FYB in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: FYB fusion protein Ag35929
• Full Name: FYN binding protein (FYB-120/130)
• Calculated Molecular Weight: 85kDa，783aa
• Observed Molecular Weight: 110 kDa
• GenBank Accession Number: NM_199335.3
• Gene Symbol: FYB
• Gene ID (NCBI): 2533
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: O15117
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

FYN binding protein (FYB-120/130), also known as FYB, ADAP (Adhesion and degranulation-promoting adapter protein), and SLAP-130 (SLP-76-associated phosphoprotein) is a protein that is encoded by the FYB gene in humans. The protein is highly expressed in T cells, NK cells, bone marrow cells, and platelets, responsible for the signal transduction upon T cell receptor (TCR) stimulation with integrin activation.