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GPX4 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 14432-1-AP

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Con: 31 μg/150 μl

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Tested Applications
Applications:
ELISA, IHC, IP, WB
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Images See all

14432-1-AP;mouse kidney tissue

mouse kidney tissue were subjected to SDS PAGE followed by western blot with 14432-1-AP(GPX4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours

14432-1-AP;mouse testis tissue

Immunohistochemistry of paraffin-embedded mouse testis tissue slide using 14432-1-AP( GPX4 antibody) at dilution of 1:100 (under 10x lens) heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

14432-1-AP;mouse testis tissue

Immunohistochemistry of paraffin-embedded mouse testis tissue slide using 14432-1-AP( GPX4 antibody) at dilution of 1:100 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

14432-1-AP;mouse kidney tissue

IP Result of anti-GPX4 (IP:14432-1-AP, 4ug; Detection:14432-1-AP 1:1000) with mouse kidney tissue lysate 4000ug.

Species specificity:
human, mouse, rat
Positive WB detected in:
mouse kidney tissue, human testis tissue, mouse kidney tissue, mouse testis tissue
Positive IP detected in:
mouse kidney tissue
Positive IHC detected in:
mouse testis tissue, human kidney tissue, human testis tissue
Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
GPX4 fusion protein Ag5809
Full name:
glutathione peroxidase 4 (phospholipid hydroperoxidase)
Calculated molecular weight:
22 kDa
Observed molecular weight:
20 kDa-23 kDa
GenBank accession number:
BC022071
Gene ID (NCBI):
2879
Gene symbol
GPX4
Synonyms
Glutathione peroxidase 4, GPx 4, GPX4, GSHPx 4, MCSP, PHGPx, snGPx, snPHGPx
Background

GPX4 (Phospholipid hydroperoxide glutathione peroxidase, mitochondrial) protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility.It has two isforms about 20KDa and 22KDa, respectively. GPX4 is a monomer,but it has a tendency to form higher mass oligomers(PMID:17630701).It presents primarily in testis.


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