HLA-G Polyclonal antibody

HLA-G Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG







Cat no : 16913-1-AP


HLA 6.0, HLA G, HLA G antigen, HLAG, HLA-G, MHC class I antigen G, MHC G

Tested Applications

Positive WB detected inhuman placenta tissue

Recommended dilution

Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 16913-1-AP is HLA-G Fusion Protein expressed in E. coli.

Tested Reactivity human
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen HLA-G fusion protein Ag10577
Full Name major histocompatibility complex, class I, G
Calculated Molecular Weight 338 aa, 38 kDa
Observed Molecular Weight 33-45 kDa
GenBank Accession NumberBC021708
Gene Symbol HLA-G
Gene ID (NCBI) 3135
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface, where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.


Product Specific Protocols
WB protocol for HLA-G antibody 16913-1-APDownload protocol
Standard Protocols
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Aging Cell

Advanced maternal age causes premature placental senescence and malformation via dysregulated α-Klotho expression in trophoblasts.

Authors - Zhi Chen

Front Immunol

Decreased USP2a Expression Inhibits Trophoblast Invasion and Associates With Recurrent Miscarriage.

Authors - Jiayu Wang

Cell Prolif

Epiregulin promotes trophoblast epithelial-mesenchymal transition through poFUT1 and O-fucosylation by poFUT1 on uPA.

Authors - Xinyuan Cui