NeutraKine® IFN Alpha 2A Monoclonal antibody

NeutraKine® IFN Alpha 2A Monoclonal Antibody for Neutralization,ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

Neutralization,ELISA

Conjugate

Unconjugated

CloneNo.

2H8G1

Cat no : 69008-1-Ig

Synonyms

IFN alpha 2, IFNA, IFNA2, IFN-alpha 2, INFA2, Interferon alpha 2, Interferon alpha A, interferon, alpha 2, LeIF A



Tested Applications

NeutralizationMeasured by its ability to neutralize Human IFN alpha 2A inhibition of growth on TF-1 cell line (human erythroleukemic cell line). The half neutralization dose (ND50) is typically 300-500 ng/mL in the presence of 100 ng/mL human INF alpha 2A.

Product Information

69008-1-Ig targets NeutraKine® IFN Alpha 2A in Neutralization,ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen human NeutraKine® IFN Alpha 2A protein HZ-1066
Full Name interferon, alpha 2
Gene symbol IFNA2
Gene ID (NCBI) 3440
Conjugate Unconjugated
Form Lyophilized Powder
Purification Method Protein G purification
Storage Buffer Sterile PBS.
Endotoxin<0.1 EU/μg
ReconstitutionThis product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
Stability and StorageLyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

Background Information

Interferon alpha 2 is a type 1 interferon. Interferon alpha 2 is secreted by virus-infected cells and inhibits other cells from further infection. Recombinant human interferon alpha 2 has been approved for therapeutic application in a range of human oncological and viral diseases. Three Interferon alpha 2 subvariants (2A, 2B, 2C) differ by only one or two amino acids at positions 23 and/or 34 of the mature protein (PMID: 25982860; 10672347; 1694761).

This antibody is used to Block/Neutralize Interferon alpha 2 protein.

Protocols

Product Specific Protocols
Neutralization protocol of NeutraKine® IFN Alpha 2A antibody 69008-1-IgDownload protocol
Standard Protocols
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