IGF1B-Specific Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 20215-1-AP

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Con: 66 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
PC-3 cells, human brain tissue

Positive IHC detected in:
human liver cancer

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
insulin-like growth factor 1 (somatomedin C)

Calculated molecular weight:
22 kDa

Observed molecular weight:
26kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IGF1

Synonyms
IGF1, Insulin like growth factor I, IGF1B, IBP1, MGF
Background

IGF1B, also named as IBP1, MGF, IGF-I and Somatomedin-C, belongs to the insulin family. IGF1 is structurally and functionally related to insulin but have a much higher growth-promoting activity. Altered expression or mutation of IGF-1 is associated with several human disorders, including type I diabetes and various forms of cancer. Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. The antibody is specific to isoform IGF-1B.


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