Mitofilin Antibody 18 Publications

Rabbit Polyclonal| Catalog number: 10179-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 37 μg/150 μl

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Species specificity:
human, mouse, hamster, rat

Positive WB detected in:
multi-cells/tissue, COLO 320 cells, HEK-293 cells, HeLa cells, HepG2 cells, human brain tissue, MCF-7 cells, Raji cells

Positive IP detected in:
Raji cells

Positive IHC detected in:
human gliomas tissue, human breast cancer tissue, human gliomas tissue

Positive IF detected in:
HeLa cells, HepG2 cells

Positive FC detected in:
HEK-293T cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
inner membrane protein, mitochondrial (mitofilin)

Calculated molecular weight:
90 kDa

Observed molecular weight:
87 kDa,89 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IMMT

Synonyms
DKFZp779P1653, HMP, IMMT, MIC60, MINOS2, Mitofilin, P87, P87/89, P89, PIG4, PIG52
Background

IMMT (also known as mitofilin) is an inner mitochondrial membrane protein that is preferentially expressed in heart tissue and is commonly used as the marker for mitochondria. Mitofilin is known to be a critical organizer of mitochondrial cristae morphology and is indispensable for normal mitochondrial function. Three isoforms of mitofilin exist due to the alternative splicing. All three proteins of 87kD, 89kD and 80kD can be detected in immunoblot analysis with this antibody.


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