|Positive WB detected in||mouse brain tissue, mouse liver tissue|
|Positive IP detected in||mouse brain tissue|
|Positive IHC detected in||human brain tissue, human testis tissue, mouse brain tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive FC detected in||HepG2 cells|
|Western Blot (WB)||WB : 1:200-1:1000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:150-1:600 for WB|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
19962-1-AP targets ITPR1-specific in WB, IP, IHC, FC,ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Full Name||inositol 1,4,5-triphosphate receptor, type 1|
|Calculated molecular weight||314 kDa|
|Observed molecular weight||290-300 kDa|
|GenBank accession number||NM_001099952|
|Gene ID (NCBI)||3708|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
ITPR1, also named as INSP3R1 and IP3R, belongs to the InsP3 receptor family. It is a receptor for inositol 1,4,5-trisphosphate which is a second messenger that mediates the release of intracellular calcium. Defects in ITPR1 are the cause of spinocerebellar ataxia type 15 (SCA15). The antibody has no cross reaction with ITPR2 and ITPR3.
|Product Specific Protocols|
|WB protocol for ITPR1-specific antibody 19962-1-AP||Download protocol|
|IHC protocol for ITPR1-specific antibody 19962-1-AP||Download protocol|
|IP protocol for ITPR1-specific antibody 19962-1-AP||Download protocol|
|FC protocol for ITPR1-specific antibody 19962-1-AP||Download protocol|
|Click here to view our Standard Protocols|
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