Anti-Human KIR2DS4/CD158i Rabbit Recombinant Antibody

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  FC experiment of human peripheral blood leukocyte using 98339-3-RR

  1x10^6 human peripheral blood leukocyte were surface stained with 0.25 ug Anti-Human KIR2DS4/CD158i Rabbit RecAb (98339-3-RR, Clone: 242656E10) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 750 Anti-Human NCAM1/CD56 Rabbit Recombinant Antibody (CL750-98033, Clone: 240078A7). Cells were not fixed.

KIR2DS4/CD158i Uni-rAb^TM Recombinant Antibody for FC

Cat No. 98339-3-RR

Clone No.242656E10

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

KIR2DS4, CD158 antigen-like family member I, CD158I, Killer cell immunoglobulin-like receptor 2DS4, KIR1D

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Tested Applications

• Positive FC detected in: human peripheral blood leukocyte

Recommended dilution

• Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension

This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

98339-3-RR targets KIR2DS4/CD158i in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: KIR2DS4/CD158i fusion protein Eg4353
• Full Name: killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
• Calculated Molecular Weight: 34 kDa
• GenBank Accession Number: NM_012314.6
• Gene Symbol: KIR2DS4
• Gene ID (NCBI): 3809
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P43632
• Storage Buffer: PBS with 0.09% sodium azide, pH 7.3.
• Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.

Background Information

KIR2DS4 (also known as CD158i) is a member of the killer cell immunoglobulin-like receptor (KIR) family. KIRs are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. KIRs are mainly involved in inhibiting NK killing (inhibitory KIRs) via interaction with MHC class I molecules. KIR2DS4 has been reported to be an activating KIR and recognize the HLA-Cw4 protein.