Product Information
98339-3-PBS targets KIR2DS4/CD158i in FC applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | KIR2DS4/CD158i fusion protein Eg4353 Predict reactive species |
Full Name | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 |
Calculated Molecular Weight | 34 kDa |
GenBank Accession Number | NM_012314.6 |
Gene Symbol | KIR2DS4 |
Gene ID (NCBI) | 3809 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P43632 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
KIR2DS4 (also known as CD158i) is a member of the killer cell immunoglobulin-like receptor (KIR) family. KIRs are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. KIRs are mainly involved in inhibiting NK killing (inhibitory KIRs) via interaction with MHC class I molecules. KIR2DS4 has been reported to be an activating KIR and recognize the HLA-Cw4 protein.