Cytokeratin 19 Antibody 25 Publications

Rabbit Polyclonal| Catalog number: 10712-1-AP

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Freight/Packing

Con: 39 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
A431 cells, A549 cells, HepG2 cells, MCF-7 cells, mouse brain tissue, mouse placenta tissue

Positive IHC detected in:
human colon tissue, human skin tissue, human liver cancer tissue, human pancreas tissue, human ovary tumor tissue, human stomach cancer tissue, human breast cancer tissue, human prostate cancer tissue, human appendix tissue, human lung cancer tissue, human prostate hyperplasia tissue, rat liver tissue, human liver tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:3000
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
keratin 19

Calculated molecular weight:
40 kDa

Observed molecular weight:
44-50 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KRT19

Synonyms
CK 19, CK19, Cytokeratin 19, K19, K1CS, keratin 19, KRT19
Background

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells. Keratin expression is highly regulated, tissue specific, and varies according to cell-state. Type I keratins consist of acidic, low molecular weight proteins with MW ranging from 40 kDa (KRT19) to 64 kDa (KRT9). Type 2 keratins consist of basic or neutral, high molecular weight proteins with MW from 52 kDa (KRT8) to 67 kDa (KRT18). Keratin 19 is a type I cytokeratin. It is a biochemical marker of skin stem cells in vivo and in vitro.


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