NEDD4 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 21698-1-AP

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Freight/Packing

Con: 33 μg/150 μl

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Species specificity:
human, mouse, rat, monkey

Positive WB detected in:
C6 cells, A549 cells, COS-7 cells, HEK-293 cells, HT-1080 cells

Positive IP detected in:
C6 cells

Positive IHC detected in:
human liver tissue, human breast cancer tissue, human lung cancer tissue

Recommended dilution:
WB : 1:500-1:2400
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
neural precursor cell expressed, developmentally down-regulated 4

Calculated molecular weight:
1319aa,149 kDa

Observed molecular weight:
115 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NEDD4

Synonyms
KIAA0093, NEDD 4, NEDD4, NEDD4 1, RPF1
Background

NEDD4-1(Neural precursor cell expressed developmentally down-regulated protein 4) is also named as NEDD4 and KIAA0093. It plays an essential role for the activation of the genetic program involved in the terminal maturation stage of invariant natural killer T-cell development(PMID:21949387). And it is differentially expressed in mammary epithelial cells and plays a role in luminal lineage determination(PMID:20351249). NEDD4-1 is a key regulator of FGFR1 endocytosis and signalling during neuronal differentiation and embryonic development(PMID:21765395). This antibody can recognize NEDD4-1 and NEDD4-2.


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