NeutraKine® PDGF-BB Monoclonal antibody

NeutraKine® PDGF-BB Monoclonal Antibody for Neutralization,ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

Neutralization,ELISA

Conjugate

Unconjugated

CloneNo.

4G11C7

Cat no : 69020-1-Ig

Synonyms

Becaplermin, c sis, FLJ12858, PDGF 2, PDGF subunit B, PDGF2, PDGFB, PDGF-BB, Proto oncogene c Sis, SIS, SSV



Tested Applications

Neutralization

Product Information

69020-1-Ig targets NeutraKine® PDGF-BB in Neutralization,ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen human NeutraKine® PDGF-BB protein HZ-1308
Full Name platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
Gene symbol PDGFB
Gene ID (NCBI) 5155
Conjugate Unconjugated
Form Lyophilized Powder
Purification Method Protein G purification
Storage Buffer Sterile PBS.
Endotoxin<0.1 EU/μg
ReconstitutionThis product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
Stability and StorageLyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

Background Information

Platelet-derived growth factor (PDGF) belongs to the family of growth factors consisting of four secreted extracellular ligands including PDGF-A, -B, -C and -D. These isoforms, PDGF-AA, PDGF-AB, PDGF-BB, PDGF-CC and PDGF-DD, act via two receptor tyrosine kinases, PDGF receptors alpha and beta. PDGF isoforms stimulate growth, survival and motility of mesenchymal cells and certain other cell type. They have important functions during embryonal development and in the control of tissue homeostasis in the adult. PDGF-BB is one of the most recently studied isoforms and it plays an important role in skeletal development. PDGF-BB stimulates cell-mediated collagen gel contraction. PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors.

This antibody is used to Block/Neutralize PDGF-BB protein.

Protocols

Product Specific Protocols
Neutralization protocol of NeutraKine® PDGF-BB antibody 69020-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols