NeutraKine® PDGF-BB Monoclonal antibody

NeutraKine® PDGF-BB Monoclonal Antibody for ELISA, Neutralization

Host / Isotype

Mouse / IgG1


Human and More (1)


ELISA, Neutralization, Cell treatment





Cat no : 69020-1-Ig


Becaplermin, c sis, FLJ12858, NeutraKine® PDGF-BB, PDGF 2, PDGF subunit B, PDGF2, PDGFB, PDGFbb, PDGF-BB, Proto oncogene c Sis, SIS, SSV


Published Applications

ELISASee 1 publications below

Product Information

69020-1-Ig targets NeutraKine® PDGF-BB in ELISA, Neutralization, Cell treatment applications and shows reactivity with Human samples.

Tested Reactivity Human
Cited Reactivityhuman
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen human Humankine PDGF-BB protein HZ-1308
Full Name platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
Gene Symbol PDGFB
Gene ID (NCBI) 5155
Conjugate Unconjugated
Form Lyophilized Powder
Purification MethodProtein A purification
Storage Buffer Sterile PBS.
Endotoxin<0.1 EU/μg
ReconstitutionThis product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
Stability and StorageLyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

Background Information

Platelet-derived growth factor (PDGF) belongs to the family of growth factors consisting of four secreted extracellular ligands including PDGF-A, -B, -C and -D. These isoforms, PDGF-AA, PDGF-AB, PDGF-BB, PDGF-CC and PDGF-DD, act via two receptor tyrosine kinases, PDGF receptors alpha and beta. PDGF isoforms stimulate growth, survival and motility of mesenchymal cells and certain other cell type. They have important functions during embryonal development and in the control of tissue homeostasis in the adult. PDGF-BB is one of the most recently studied isoforms and it plays an important role in skeletal development. PDGF-BB stimulates cell-mediated collagen gel contraction. PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors.

This antibody can be used to neutralize the bioactivity of PDGF-BB.



Free Radic Biol Med

IRF1/ZNF350/GPX4-mediated ferroptosis of renal tubular epithelial cells promote chronic renal allograft interstitial fibrosis

Authors - Yao Zhang
humanCell treatment


Hepatocyte Ninjurin2 promotes hepatic stellate cell activation and liver fibrosis through the IGF1R/EGR1/PDGF-BB signaling pathway

Authors - Yifan Wang